Liver-specific magnetic resonance contrast medium in the evaluation of chronic liver disease

Liver-specific magnetic resonance contrast medium in the evaluation of chronic liver disease

The hepatobiliary-specific contrast medium (gadoxetic acid - Primovist®) is primarily used to improve detection and characterization of focal hepatic lesions, such as in chronic liver disease patients with suspected hepatocellular carcinoma. Since the contrast medium is selectively taken up by functioning hepatocytes in the late hepatobiliary phase, it helps to detect typical hepatocellular car...

Utility of Modeling End-Stage Liver Disease in Children with Chronic Liver Disease

Introduction: Chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. The pediatric end-stage liver disease (PELD) score and model of end-stage liver disease (MELD) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. The aim of this study is evaluation of relation be...

Applications of magnetic resonance spectroscopy to chronic liver disease.

In vivo magnetic resonance spectroscopy (MRS) provides a non-invasive 'window' on biochemical processes within the body. The technique is currently a research tool, but new developments in whole-body magnetic resonance imaging (MRI) may provide a role for clinical MRS in obtaining functional information at the end of a standard MRI examination. Applications of hepatic and cerebral MRS to chroni...

Contrast-enhanced magnetic resonance liver image registration, segmentation, and feature analysis for liver disease diagnosis

Magnetic resonance of the liver with hepato-specific contrast: initial clinical experience in Brazil.

The authors report the initial clinical experience of gadoxetic acid as a liver-specific magnetic resonance (MR) imaging contrast mediumin a private clinic in Brasil. This substance, which was recently approved for clinical use in the country, shows specific uptake by the hepatocytes, reaching a concentration peak around 10-20 minutes post-injection. Among the main indications for the use of th...